Estramustine [2998-57-4]

MedChem Express

Estramustine [2998-57-4]

10

2998-57-4

Research Use Only

99.15

C23H31Cl2NO3

440.40

Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 microM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts[1].

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC(N(CCCl)CCCl)=O)C=C4CC3

2°C to 8°C

12352200