Estrogen Receptor alpha antibody
GTX14020
ApplicationsWestern Blot
Product group Antibodies
TargetESR1
Overview
- SupplierGeneTex
- Product NameEstrogen Receptor alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2099
- Target nameESR1
- Target descriptionestrogen receptor 1
- Target synonymsER, ESR, ESRA, ESTRR, Era, NR3A1, estrogen receptor, E2 receptor alpha, ER-alpha, estradiol receptor, estrogen nuclear receptor alpha, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, nuclear receptor subfamily 3 group A member 1, oestrogen receptor alpha
- HostChicken
- IsotypeIgY
- Protein IDP03372
- Protein NameEstrogen receptor
- Scientific DescriptionThis antibody recognizes human ER-alpha, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-alpha can positively or negatively regulate gene transcription.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203


![IHC-P analysis of human breast carcinoma tissue using GTX17904 Estrogen Receptor alpha antibody [ESR1/1935].](https://www.genetex.com/upload/website/prouct_img/normal/GTX17904/GTX17904_20200115_IHC-P_355_w_23060620_163.webp)
![WB analysis of full-length human ER alpha recombinant protein and ER beta protein using GTX22746 Estrogen Receptor alpha antibody [33] at 4 microg/ml (left panel) or GTX25786 Estrogen Receptor beta antibody at 1:2000 (right panel).](https://www.genetex.com/upload/website/prouct_img/normal/GTX22746/GTX22746_1582_WB_w_23060620_315.webp)




![ChIP analysis of sheared chromatin from MCF7 cells treated for 1 hour with estradiol using GTX60340 Estrogen Receptor alpha antibody [GT9004]. The IPd DNA was analysed with an Illumina Genome Analyzer. Library preparation, cluster generation and sequencing were performed according to the manufacturers instructions. The 36 bp tags were aligned to the human genome using the ELAND algorithm. This figure shows the obtained peaks near the TFF1 gene on chromosome 21 (figure 1A), the GREB1 and HAAO genes on chromosome 2 (figure 1B and C), and the ZNF185 gene on the X-chromosome (figure 1D).](https://www.genetex.com/upload/website/prouct_img/normal/GTX60340/GTX60340_20201117_ChIP_64_w_23061123_131.webp)