IHC-P analysis of human breast cancer tissue using GTX41213 Estrogen Receptor beta 2 antibody. Antigen retrieval using citrate buffer at pH6.2.
Estrogen Receptor beta 2 antibody [57/3]
GTX41213
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetESR2
Overview
- SupplierGeneTex
- Product NameEstrogen Receptor beta 2 antibody [57/3]
- Delivery Days Customer9
- Antibody SpecificityThis antibody recognizes the estrogen receptor beta 2 isoform. No cross-reactivity is seen with estrogen receptor beta 1 isoform.
- Application Supplier NoteIHC-P: 1/50-1/500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID57/3
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2100
- Target nameESR2
- Target descriptionestrogen receptor 2
- Target synonymsErb; ER-BETA; ESRB; ESR-BETA; ESTRB; estrogen receptor beta; estrogen receptor beta 4; estrogen receptor beta splice variant, ERbeta2delta7; estrogen receptor beta splice variant, ERbeta4delta7; estrogen receptor beta splice variant, ERbeta6; estrogen receptor beta splice variant, ERbeta6delta7; estrogen receptor beta splice variant, ERbeta7; estrogen receptor beta splice variant, ERbeta7delta7; estrogen receptor beta splice variant, ERbetaEx. 4L; estrogen receptor beta splice variant, ERbetaEx. 6L; NR3A2; nuclear receptor subfamily 3 group A member 2; ODG8; oestrogen receptor beta
- HostMouse
- IsotypeIgG1
- Protein IDQ92731
- Protein NameEstrogen receptor beta
- Scientific DescriptionThis gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203