Ethacrynic acid D5

Biorbyt

Ethacrynic acid D5

10

1330052-59-9

Research Use Only

98.00%

C13H12Cl2O4

308.17

Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by its deuterium labeling.

C(C(C(C([2H])([2H])[2H])([2H])[2H])=C)(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1

-20°C

12352200