Western blot All lanes: ETHE1 antibody at 8microg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa
Western blot All lanes: ETHE1 antibody at 8microg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa
ETHE1 Antibody
CSB-PA007847HA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetETHE1
Overview
- SupplierCusabio
- Product NameETHE1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23474
- Target nameETHE1
- Target descriptionETHE1 persulfide dioxygenase
- Target synonymsHSCO, YF13H12, persulfide dioxygenase ETHE1, mitochondrial, ethylmalonic encephalopathy 1, hepatoma subtracted clone one protein, protein ETHE1, mitochondrial, sulfur dioxygenase ETHE1
- HostRabbit
- IsotypeIgG
- Protein IDO95571
- Protein NamePersulfide dioxygenase ETHE1, mitochondrial
- Scientific DescriptionSulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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