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Western blot All lanes: ETHE1 antibody at 8microg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa
Western blot All lanes: ETHE1 antibody at 8microg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa
Western blot All lanes: ETHE1 antibody at 8microg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa

ETHE1 Antibody

CSB-PA007847HA01HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetETHE1
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Overview

  • Supplier
    Cusabio
  • Product Name
    ETHE1 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID23474
  • Target name
    ETHE1
  • Target description
    ETHE1 persulfide dioxygenase
  • Target synonyms
    ethylmalonic encephalopathy 1; hepatoma subtracted clone one protein; HSCO; persulfide dioxygenase ETHE1, mitochondrial; protein ETHE1, mitochondrial; sulfur dioxygenase ETHE1; YF13H12
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95571
  • Protein Name
    Persulfide dioxygenase ETHE1, mitochondrial
  • Scientific Description
    Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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