Ethonafide

MedChem Express

Ethonafide

9

Research Use Only

C22H22N2O3

362.42

Ethonafide (AMP-53) is an anthracene-containing derivative of Amonafide that belongs to the Azonafide series of anticancer agents. Ethonafide (AMP-53) inhibits topoisomerase II activity by stabilizing the enzyme-DNA complex, involving both topoisomerase IIalpha and beta[1].

O=C1N(CCN(C)C)C(C2=CC=C(OCC)C3=CC4=CC=CC=C4C1=C23)=O

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