Etilefrine [709-55-7]

MedChem Express

Etilefrine [709-55-7]

5

709-55-7

Research Use Only

97.03

C10H15NO2

181.23

Etilefrine is a sympathetic nerve agonist and AMPK activator that selectively targets alpha1/beta1 adrenergic receptors. Etilefrine stimulates alpha1 adrenergic receptors, leading to contraction of vascular smooth muscle and increased peripheral resistance. Etilefrine also stimulates beta1 receptors to enhance myocardial contractility and increase heart rate, thereby increasing blood pressure and improving cardiac output. Etilefrine also bidirectionally regulates the AMPK/Akt pathway and modulates the phosphorylation levels. Etilefrine can be used in cardiovascular research, such as postural hypotension, chylothorax, and improving low cardiac output[1][2][3].

OC(CNCC)C1=CC=CC(O)=C1

-20°C,2°C to 8°C

12352200