ETS2 antibody
GTX104527
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetETS2
Overview
- SupplierGeneTex
- Product NameETS2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.35 mg/ml
- ConjugateUnconjugated
- Gene ID2114
- Target nameETS2
- Target descriptionETS proto-oncogene 2, transcription factor
- Target synonymsETS2IT1, protein C-ets-2, oncogene ETS-2, v-ets avian erythroblastosis virus E2 oncogene homolog 2, v-ets avian erythroblastosis virus E26 oncogene homolog 2, v-ets erythroblastosis virus E26 oncogene homolog 2
- HostRabbit
- IsotypeIgG
- Protein IDP15036
- Protein NameProtein C-ets-2
- Scientific DescriptionETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kishimoto Y, Nishiura I, Hirata W, et al. A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models. Sci Rep. 2021,11(1):8297. doi: 10.1038/s41598-021-87751-5Read this paper
- Gluck C, Glathar A, Tsompana M, et al. Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma. PLoS Genet. 2019,15(7):e1008250. doi: 10.1371/journal.pgen.1008250Read this paper
- Helbig S, Wockner L, Bouendeu A, et al. Functional dissection of breast cancer risk-associated TERT promoter variants. Oncotarget. 2017,8(40):67203-67217. doi: 10.18632/oncotarget.18226Read this paper
- Yuan J, Jiang YY, Mayakonda A, et al. Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma. Cancer Res. 2017,77(23):6614-6626. doi: 10.1158/0008-5472.CAN-17-1143Read this paper
Datasheet
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