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ProductsBack/ETS2 antibody

ETS2 antibody

GTX104527
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetETS2
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Overview

  • Supplier
    GeneTex
  • Product Name
    ETS2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.35 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2114
  • Target name
    ETS2
  • Target description
    ETS proto-oncogene 2, transcription factor
  • Target synonyms
    ETS2IT1; oncogene ETS-2; protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15036
  • Protein Name
    Protein C-ets-2
  • Scientific Description
    ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models. Kishimoto Y et al., 2021 Apr 15, Sci Rep
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  • Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma. Gluck C et al., 2019 Jul, PLoS Genet
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  • Functional dissection of breast cancer risk-associated TERT promoter variants. Helbig S et al., 2017 Sep 15, Oncotarget
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  • Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma. Yuan J et al., 2017 Dec 1, Cancer Res
    Read more