Overview
- SupplierGeneTex
- Product NameETS2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.35 mg/ml
- IsotypeIgG
- Scientific DescriptionETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models. Kishimoto Y et al., 2021 Apr 15, Sci RepRead more
- Functional dissection of breast cancer risk-associated TERT promoter variants. Helbig S et al., 2017 Sep 15, OncotargetRead more
- Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma. Gluck C et al., 2019 Jul, PLoS GenetRead more
- Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma. Yuan J et al., 2017 Dec 1, Cancer ResRead more