Evogliptin (hydrochloride) [1246960-27-9]

MedChem Express

Evogliptin (hydrochloride) [1246960-27-9]

5

1246960-27-9

Research Use Only

C19H27ClF3N3O3

437.88

Evogliptin hydrochloride (DA-1229 hydrochloride) is an orally available DPP4 inhibitor with significant and durable hypoglycemic effects in mouse models. Evogliptin hydrochloride also inhibits the generation of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin hydrochloride can be used in the research of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation[1].

O=C1NCCN([C@@H]1COC(C)(C)C)C(C[C@@H](CC2=CC(F)=C(C=C2F)F)N)=O.Cl

12352200