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CgoaEGY7OWaEVx3cAAAAALJJz5s149.png

Exatecan [171335-80-1]

Research Use Only
T11249
TargetMol Chemicals
CAS Number171335-80-1
DownloadMSDS
Product group Chemicals
Molecular Weight435.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Exatecan [171335-80-1]
  • Delivery Days Customer
    9
  • CAS Number
    171335-80-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Exatecan
  • Molecular Formula
    C24H22FN3O4
  • Molecular Weight
    435.45
  • Scientific Description
    Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 microM (0.975 microg/mL).Exatecan has antitumor activity and may be used in cancer research.
  • Shelf life instruction
    3 years
  • SMILES
    N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.
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