Exatecan intermediate 11

MedChem Express

Exatecan intermediate 11

14

Research Use Only

C13H13FN2O3

264.25

Exatecan intermediate 11 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 microM)[1].

CC1=C2C(C(/C(CC2)=N\O)=O)=C(NC(C)=O)C=C1F

41115800