Exatecan Intermediate 5 [143655-70-3]

TargetMol Chemicals

Exatecan Intermediate 5 [143655-70-3]

9

143655-70-3

Research Use Only

C15H17FN2O3

292.31

Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 microM (0.975 microg/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs).

O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C

-20°C

12352200