EXD2 Polyclonal Antibody
RD218841A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetEXD2
Overview
- SupplierReddot Biotech
- Product NameEXD2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.96 mg/ml
- ConjugateUnconjugated
- Gene ID55218
- Target nameEXD2
- Target descriptionexonuclease 3'-5' domain containing 2
- Target synonyms3'-5' exoribonuclease EXD2; C14orf114; EXDL2; exonuclease 3'-5' domain-containing protein 2; exonuclease 3'-5' domain-like 2; exonuclease 3'-5' domain-like-containing protein 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionExonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3-5 exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203