Exicorilant [1781244-77-6]

MedChem Express

Exicorilant [1781244-77-6]

5

1781244-77-6

Research Use Only

99.48

C26H23F4N7O3S

589.56

Exicorilant (CORT 125281) is a selective and oral active glucocorticoid receptor (GR) antagonist, with a Ki value of 7 nM[1]. Exicorilant (CORT 125281) has potential to overcome adiposity, glucose intolerance and dyslipidaemia[2].

O=C([C@]12CC3=C(N(C4=CC=C(F)C=C4)N=C3)C[C@]1([H])CCN(S(=O)(C5=NN(C)N=C5)=O)C2)C6=NC=CC(C(F)(F)F)=C6

-20°C,2°C to 8°C

12352200