Western blot analysis of extracts of various cell lines using EXOC2 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using EXOC2 Polyclonal Antibody at dilution of 1:1000.
EXOC2 Polyclonal Antibody
E-AB-63135
Product group Antibodies
Overview
- SupplierElabscience
- Product NameEXOC2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
- UNSPSC12352203