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ProductsBack/EYA2 Antibody

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007907LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007907LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007907LA01HU at dilution of 1:100

EYA2 Antibody

CSB-PA007907LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetEYA2

Overview

Supplier
Cusabio
Product Name
EYA2 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID2139
Target name
EYA2
Target description
EYA transcriptional coactivator and phosphatase 2
Target synonyms
EAB1, protein phosphatase EYA2, eyes absent homolog 2
Host
Rabbit
Isotype
IgG
Protein IDO00167
Protein Name
Protein phosphatase EYA2
Scientific Description
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates Tyr-142 of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. Tyr-142 phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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