EYE-002
HY-175663
Molecular Weight311.37
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameEYE-002
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC16H25NO5
- Molecular Weight311.37
- Scientific DescriptionEYE-002 is a RPE65 inhibitor with an IC50 of 69 nM. EYE-002 promotes recovery of scotopic ERG a-/b-wave amplitudes. EYE-002 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-002 exerts protective effects against photic retinal damage in mice. EYE-002 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1)[1].
- SMILESO=CO.CCC(CC)C(OC1=CC=CC(C(O)CCN)=C1)=O
- UNSPSC12352200