(E/Z)-BIO-acetoxime [740841-15-0]

MedChem Express

(E/Z)-BIO-acetoxime [740841-15-0]

10

740841-15-0

Research Use Only

99.0

C18H12BrN3O3

398.21

(E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3alpha/beta inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 microM)[1].

CC(O/N=C1/C(NC2=C1C=CC=C2)=C3C(NC4=C\3C=CC(Br)=C4)=O)=O

-20°C,2°C to 8°C

12352200