(E/Z)-GO289 [694522-87-7]

TargetMol Chemicals

(E/Z)-GO289

4

694522-87-7

Chemical

Research Use Only

(E/Z)-GO289

99.68%

C17H15BrN4O2S

419.3

(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.

3 years

COc1cc(\C=N\n2c(SC)nnc2-c2ccccc2)c(Br)cc1O

-20°C

12352200