(E/Z)-GSK5182

MedChem Express

(E/Z)-GSK5182

9

Research Use Only

98.90

C27H31NO3

417.54

(E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers. GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor gamma (ERRgamma) with an IC50 of 79 nM[1]. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma[1][2][3].

OCCC/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)OCCN(C)C)\C3=CC=C(C=C3)O

-20°C,2°C to 8°C

12352200