(E/Z)-IT-603

MedChem Express

(E/Z)-IT-603 [292168-90-2]

10

292168-90-2

Research Use Only

99.91

C11H9BrN2O3S

329.17

(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). (E/Z)-IT-603 is also an IkappaBalpha/c-Rel inhibitor. IT-603 is a c-Rel inhibitor with an IC 50 of 3 microM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases [1] .

O=C(/C(N1)=C\C2=CC(Br)=CC(OC)=C2O)NC1=S

-20°C,2°C to 8°C

12352200