(E/Z)-THZ1 (dihydrochloride) [2095433-94-4]

MedChem Express

(E/Z)-THZ1 (dihydrochloride) [2095433-94-4]

14

2095433-94-4

Research Use Only

C31H30Cl3N7O2

638.97

(E/Z)-THZ1 dihydrochloride is a selective inhibitor of CDK7 with an IC50 of 3.2 nM. (E/Z)-THZ1 dihydrochloride has antiproliferative effect[1][2].

O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5.[H]Cl.[H]Cl

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