(E/Z)-Zotiraciclib [937270-47-8] [937270-47-8]
T21503
CAS Number937270-47-8
Product group Chemicals
Estimated Purity≥95%
Molecular Weight372.46
Overview
- SupplierTargetMol Chemicals
- Product Name(E/Z)-Zotiraciclib [937270-47-8] [937270-47-8]
- Delivery Days Customer4
- CAS Number937270-47-8
- CertificationResearch Use Only
- Chemical Name(E/Z)-Zotiraciclib
- Estimated Purity≥95%
- Molecular FormulaC23H24N4O
- Molecular Weight372.46
- Scientific Description(E/Z)-Zotiraciclib ((E/Z)-TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13
- Shelf life instruction3 years
- SMILESCN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2
- Storage Instruction-20°C
- UNSPSC12352200
References
- Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer.Read this paper
MSDS
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