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EZH2 antibody

Name: EZH2 antibody
SKU: GTX110384_G10
Availability: BackOrder

GTX110384

ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman, Rat

TargetEZH2

Overview

Supplier
GeneTex
Product Name
EZH2 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.42 mg/ml
Conjugate
Unconjugated
Gene ID2146
Target name
EZH2
Target description
enhancer of zeste 2 polycomb repressive complex 2 subunit
Target synonyms
ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2, histone-lysine N-methyltransferase EZH2, enhancer of zeste homolog 2, lysine N-methyltransferase 6
Host
Rabbit
Isotype
IgG
Protein IDQ15910
Protein Name
Histone-lysine N-methyltransferase EZH2
Scientific Description
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Reactivity
Human, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Qian X, Zhang Y. EZH2 enhances proliferation and migration of trophoblast cell lines by blocking GADD45A-mediated p38/MAPK signaling pathway. Bioengineered. 2022,13(5):12583-12597. doi: 10.1080/21655979.2022.2074620
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Liao X, Zhou Z, Zhang X. Effects of miR‑195‑5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2. Mol Med Rep. 2020,22(2):803-809. doi: 10.3892/mmr.2020.11142
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Blin G, Liand M, Mauduit C, et al. Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the Heart. Nutrients. 2020,12(1). doi: 10.3390/nu12010181
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Yang PM, Hong YH, Hsu KC, et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma. Am J Cancer Res. 2019,9(10):2120-2139.
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