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EZH2 antibody

GTX110384
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
TargetEZH2
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Overview

  • Supplier
    GeneTex
  • Product Name
    EZH2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.42 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2146
  • Target name
    EZH2
  • Target description
    enhancer of zeste 2 polycomb repressive complex 2 subunit
  • Target synonyms
    enhancer of zeste homolog 2; ENX1; ENX-1; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; WVS; WVS2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15910
  • Protein Name
    Histone-lysine N-methyltransferase EZH2
  • Scientific Description
    This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • EZH2 enhances proliferation and migration of trophoblast cell lines by blocking GADD45A-mediated p38/MAPK signaling pathway.
    Read more
  • Effects of miR-195-5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2. Liao X et al., 2020 Aug, Mol Med Rep
    Read more
  • Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the Heart. Blin G et al., 2020 Jan 9, Nutrients
    Read more
  • p38alpha/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma. Yang PM et al., 2019, Am J Cancer Res
    Read more

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