EZH2-IN-16 [2238820-26-1]

MedChem Express

EZH2-IN-16 [2238820-26-1]

5

2238820-26-1

Research Use Only

C32H38N4O4

542.67

EZH2-IN-16 (Compound 24) is an inhibitor for histone methyltransferase (EZH2). EZH2-IN-16 inhibits EZH2 and EZH2 Y641F, with IC50 of 37.6 and 79.1 nM. EZH2-IN-16 inhibits proliferation of WSU-DLCL2, with GI50 of 0.2 microM[1].

O=C(C1=CC(C2=CC=C(N3CCOCC3)C=C2)=CC(N(CC)C(C4CC4)=O)=C1C)NCC5=C(C)C=C(C)NC5=O

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