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EZM 2302 [1628830-21-6]

EZM 2302 [1628830-21-6]

T5605
TargetMol Chemicals
CAS Number1628830-21-6
Product group Chemicals
Estimated Purity0.9747
Molecular Weight585.09
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    EZM 2302 [1628830-21-6]
  • Delivery Days Customer
    4
  • CAS Number
    1628830-21-6
  • Certification
    Research Use Only
  • Chemical Name
    EZM 2302
  • Estimated Purity
    0.9747
  • Molecular Formula
    C29H37ClN6O5
  • Molecular Weight
    585.09
  • Scientific Description
    EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).[1]
  • Shelf life instruction
    3 years
  • SMILES
    CNC[C@@H](O)COc1ccc(Cl)c(c1)-c1nc(N2CC3(C2)CCN(CC3)C(=O)OC)c(C)c(n1)-c1c(C)noc1C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Drew AE, Moradei O, Jacques SL, et al. Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma. Sci Rep. 2017,7(1):17993. doi: 10.1038/s41598-017-18446-z
    Read this paper

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