FABP3 Protein (OPPA01255)

Aviva Systems Biology

FABP3 Protein (OPPA01255)

23

Research Use Only

>90%

50mM phosphate borate buffer pH-8. Physical appearance: Sterile filtered liquid formulation.

Fatty acid-binding protein, heart

Recombinant Fatty Acid Binding Protein is a newly introduced plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. But the concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), that makes FABP to be more cardiac specific than myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of myocardial infarct size.

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