FABP4 (human) (rec.) (His)
AG-40A-0035
Overview
- SupplierAdipoGen Life Sciences
- Product NameFABP4 (human) (rec.) (His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration1 mg/ml
- Estimated Purity>90%
- FormulationLiquid
- Protein IDP15090
- Protein NameFatty acid-binding protein, adipocyte
- Scientific DescriptionFABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. aP2, the mouse form of FABP4, seems to be central to the pathway that links obesity to insulin resistance. aP2 was shown to be an adipokine linking adipocytes to hepatic glucose production and that neutralizing secreted aP2 may represent an effective therapeutic strategy against diabetes. - Protein. Human FABP4 (aa 1-132) is fused at the C-terminus to a His-tag. Source: E. coli. Endotoxin content: <1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 200mM NaCl. Purity: >90% (SDS-PAGE). FABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. aP2, the mouse form of FABP4, seems to be central to the pathway that links obesity to insulin resistance. aP2 was shown to be an adipokine linking adipocytes to hepatic glucose production and that neutralizing secreted aP2 may represent an effective therapeutic strategy against diabetes.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202