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Factor IX antibody [N3C3]

GTX113689
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetF9
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Overview

  • Supplier
    GeneTex
  • Product Name
    Factor IX antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2158
  • Target name
    F9
  • Target description
    coagulation factor IX
  • Target synonyms
    Christmas factor; coagulation factor IX; F9 p22; factor 9; factor IX F9; FIX; HEMB; P19; plasma thromboplastic component; plasma thromboplastin component; PTC; THPH8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00740
  • Protein Name
    Coagulation factor IX
  • Scientific Description
    This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Development of a sandwich enzyme-linked immunosorbent assay (ELISA) to quantify gamma-glutamyl-carboxylated clotting factor IX and assess redox susceptibility of anticoagulant chemicals.
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