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Human Factor Xa activity is inhibited by Rivaroxaban. (96 reactions)
Human Factor Xa activity is inhibited by Rivaroxaban. (96 reactions)
Human Factor Xa activity is inhibited by Rivaroxaban. (96 reactions)

Factor Xa Inhibitor Screening Assay Kit

Research Use Only
78868
BPS Bioscience
Product group Assays
Price on request
Packing Size
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Order with a bulk request

Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Factor Xa Inhibitor Screening Assay Kit
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    The Factor Xa Inhibitor Screening Assay is a colorimetric assay designed to measure the activity of human Factor Xa for screening and profiling applications. The assay kit comes in a convenient 96-well format or 384-well format and contains enough purified human Factor Xa, a chromogenic substrate, and PR-02 buffer for 100 or 400 reactions. To determine the effect of an inhibitor on Factor Xa activity, the enzyme should be preincubated with or without the test inhibitor prior to adding the chromogenic substrate to the reaction. The assay was functionally validated using Rivaroxaban, a potent inhibitor of Factor Xa. Upon proteolysis, Factor Xa cleaves the chromogenic substrate at the C-terminal end releasing p-nitroanilid (pNA), which produces a yellow color that is measurable photometrically at lambda=405 nm. The increase in color is proportional to Factor Xa activity.
  • Storage Instruction
    See manual
  • UNSPSC
    41116133