FADD antibody [1C11]

GeneTex

FADD antibody [1C11]

9

WB: 1:2000. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot

Research Use Only

Monoclonal

1C11

1 mg/ml

Unconjugated

FADD

Fas associated via death domain

GIG3, IMD90, MORT1, FAS-associated death domain protein, Fas (TNFRSF6)-associated via death domain, Fas-associating death domain-containing protein, Fas-associating protein with death domain, growth-inhibiting gene 3 protein, mediator of receptor-induced toxicity

Mouse

IgG1

FAS-associated death domain protein

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Human

-20°C or -80°C,2°C to 8°C

12352203