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Western Blot analysis of Mouse spleen tissue and RAW264.7 cell using FADD Polyclonal Antibody at dilution of 1:550
Western Blot analysis of Mouse spleen tissue and RAW264.7 cell using FADD Polyclonal Antibody at dilution of 1:550
Western Blot analysis of Mouse spleen tissue and RAW264.7 cell using FADD Polyclonal Antibody at dilution of 1:550

FADD Polyclonal Antibody

Research Use Only
E-AB-10318
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    FADD Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.5mg/ml
  • Scientific Description
    The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
  • UNSPSC
    12352203