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FAK antibody

GTX100764
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPTK2
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Overview

  • Supplier
    GeneTex
  • Product Name
    FAK antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.26 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5747
  • Target name
    PTK2
  • Target description
    protein tyrosine kinase 2
  • Target synonyms
    FADK; FADK 1; FAK; FAK1; FAK-related non-kinase polypeptide; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; PTK2 protein tyrosine kinase 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ05397
  • Protein Name
    Focal adhesion kinase 1
  • Scientific Description
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition.
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  • Synergistic Combination of Luteolin and Asiatic Acid on Cervical Cancer In Vitro and In Vivo.
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  • Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2.
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  • Anticancer Effects and Molecular Mechanisms of Apigenin in Cervical Cancer Cells. Chen YH et al., 2022 Apr 4, Cancers (Basel)
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  • Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin. Yang YC et al., 2016 May 10, Oncotarget
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  • Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma. Chiang WF et al., 2013 Jun, Oral Oncol
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  • Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Hsu HY et al., 2012, Evid Based Complement Alternat Med
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