FAK antibody
GTX100764
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPTK2
Overview
- SupplierGeneTex
- Product NameFAK antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.26 mg/ml
- ConjugateUnconjugated
- Gene ID5747
- Target namePTK2
- Target descriptionprotein tyrosine kinase 2
- Target synonymsFADK, FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, focal adhesion kinase 1, FAK-related non-kinase polypeptide, PTK2 protein tyrosine kinase 2, focal adhesion kinase-related nonkinase, protein phosphatase 1 regulatory subunit 71
- HostRabbit
- IsotypeIgG
- Protein IDQ05397
- Protein NameFocal adhesion kinase 1
- Scientific DescriptionThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Liao WL, Liu YF, Ying TH, et al. Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2. Int J Mol Sci. 2022,24(1). doi: 10.3390/ijms24010366Read this paper
- Chen YH, Wu JX, Yang SF, et al. Anticancer Effects and Molecular Mechanisms of Apigenin in Cervical Cancer Cells. Cancers (Basel). 2022,14(7). doi: 10.3390/cancers14071824Read this paper
- Yang YC, Chin YT, Hsieh MT, et al. Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin. Oncotarget. 2016,7(19):27641-54. doi: 10.18632/oncotarget.8505Read this paper
- Chiang WF, Hwang TZ, Hour TC, et al. Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma. Oral Oncol. 2013,49(6):534-41. doi: 10.1016/j.oraloncology.2013.01.003Read this paper
- Hsu HY, Lin JH, Li CJ, et al. Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Evid Based Complement Alternat Med. 2012,2012:819632. doi: 10.1155/2012/819632Read this paper



![ICC/IF analysis of B16 cells using GTX82780 FAK antibody [10H7]. Green : FAK Blue: DRAQ5 fluorescent DNA dye](https://www.genetex.com/upload/website/prouct_img/normal/GTX82780/GTX82780_20170912_ICCIF_w_23061322_525.webp)
![FACS analysis of Raji cells using GTX83323 FAK antibody [10H7E9]. Green : FAK Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX83323/GTX83323_20170912_FACS_w_23061322_838.webp)
![WB analysis of FAK(AA: 354-533)-hIgGFc transfected HEK293 cell lysate using GTX83324 FAK antibody [10H7A6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83324/GTX83324_20170912_WB_w_23061322_756.webp)
