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FAK antibody

GTX100764
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPTK2
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Overview

  • Supplier
    GeneTex
  • Product Name
    FAK antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.26 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5747
  • Target name
    PTK2
  • Target description
    protein tyrosine kinase 2
  • Target synonyms
    FADK, FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, focal adhesion kinase 1, FAK-related non-kinase polypeptide, PTK2 protein tyrosine kinase 2, focal adhesion kinase-related nonkinase, protein phosphatase 1 regulatory subunit 71
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ05397
  • Protein Name
    Focal adhesion kinase 1
  • Scientific Description
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Hsu HY, Lin JH, Li CJ, et al. Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Evid Based Complement Alternat Med. 2012,2012:819632. doi: 10.1155/2012/819632
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