FAK inhibitor 7

Biorbyt

FAK inhibitor 7

10

Research Use Only

98.00%

C32H37N7O3

567.68

FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.

O=C1C=2C(OC3=NC(=NC=4NC=CC34)NC5=CC=C(C=C5OC)N6CCC(N7CCN(C)CC7)CC6)=CC=CC2CC1

-20°C

12352200