Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: FAM20C antibody at 4.1microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 67, 30 kDa Observed band size: 67 kDa
Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: FAM20C antibody at 4.1microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 67, 30 kDa Observed band size: 67 kDa
FAM20C Antibody
CSB-PA816901LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFAM20C
Overview
- SupplierCusabio
- Product NameFAM20C Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID56975
- Target nameFAM20C
- Target descriptionFAM20C golgi associated secretory pathway kinase
- Target synonymsDMP-4, DMP4, G-CK, GEF-CK, RNS, extracellular serine/threonine protein kinase FAM20C, Golgi casein kinase, dentin matrix protein 4, family with sequence similarity 20, member C, golgi-enriched fraction casein kinase
- HostRabbit
- IsotypeIgG
- Protein IDQ8IXL6
- Protein NameExtracellular serine/threonine protein kinase FAM20C
- Scientific DescriptionGolgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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