Famitinib (malate) [1256377-67-9]

MedChem Express

Famitinib (malate) [1256377-67-9]

10

1256377-67-9

Research Use Only

C27H33FN4O7

544.58

Famitinib (SHR1020) malate, an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit, VEGFR-2 and PDGFRbeta with IC50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively. Famitinib malate induces cell apoptosis. Famitinib malate exerts powerful antitumor activity in human gastric cancer cells and xenografts, it can be used for the research of cancer[1][2].

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