Immunofluorescence staining of A549 cells with CSB-PA889120LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

FANCI Antibody

CSB-PA889120LA01HU

ApplicationsImmunoFluorescence, ELISA

Product group Antibodies

ReactivityHuman

TargetFANCI

Overview

Supplier
Cusabio
Product Name
FANCI Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID55215
Target name
FANCI
Target description
FA complementation group I
Target synonyms
KIAA1794, Fanconi anemia group I protein, Fanconi anemia complementation group I
Host
Rabbit
Isotype
IgG
Protein IDQ9NVI1
Protein Name
Fanconi anemia group I protein
Scientific Description
Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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FANCI Antibody

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