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Fas Ligand antibody [NOK-1]

Research Use Only
GTX01476
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetFASLG
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Fas Ligand antibody [NOK-1]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    NOK-1
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID356
  • Target name
    FASLG
  • Target description
    Fas ligand
  • Target synonyms
    ALPS1B; apoptosis (APO-1) antigen ligand 1; apoptosis antigen ligand; APT1LG1; APTL; CD178; CD95 ligand; CD95L; CD95-L; fas antigen ligand; Fas ligand (TNF superfamily, member 6); FASL; mutant tumor necrosis factor family member 6; TNFSF6; TNLG1A; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Fatty Acid Synthase Contributes to Restimulation-Induced Cell Death of Human CD4 T Cells. Voss K et al., 2019, Front Mol Biosci
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  • Metalloproteinase-mediated release of human Fas ligand. Kayagaki N et al., 1995 Dec 1, J Exp Med
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