FAS Monoclonal Antibody

Reddot Biotech

FAS Monoclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Monoclonal

10E5B10

420 ug/ml

Unconjugated

FAS

Fas cell surface death receptor

ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, tumor necrosis factor receptor superfamily member 6, APO-1 cell surface antigen, CD95 antigen, FASLG receptor, Fas (TNF receptor superfamily, member 6), Fas AMA, TNF receptor superfamily member 6, apoptosis antigen 1, apoptosis signaling receptor FAS, apoptosis-mediating surface antigen FAS, mutant tumor necrosis receptor superfamily member 6, tumor necrosis factor receptor superfamily, member 6

Mouse

IgG

Tumor necrosis factor receptor superfamily member 6

FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand. - This is a FAS Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Human, Mouse

-20°C

41116161