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ProductsBack/Fasudil [103745-39-7]

Fasudil [103745-39-7]

Research Use Only
HY-10341A
MedChem Express
CAS Number103745-39-7
Product group Chemicals
Molecular Weight291.37
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fasudil [103745-39-7]
  • Delivery Days Customer
    10
  • CAS Number
    103745-39-7
  • Certification
    Research Use Only
  • Molecular Formula
    C14H17N3O2S
  • Molecular Weight
    291.37
  • Scientific Description
    Fasudil (HA-1077; AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 microM for ROCK1, IC50s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
  • SMILES
    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O
  • UNSPSC
    12352200