Fasudil (Hydrochloride)

MedChem Express

Fasudil (Hydrochloride) [105628-07-7]

10

105628-07-7

Research Use Only

99.96

C14H18ClN3O2S

327.83

Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 microM for ROCK1 , IC 50 s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil Hydrochloride is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3] .

O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]

2°C to 8°C

12352200