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ProductsBack/Fasudil (Hydrochloride) [105628-07-7]

Fasudil (Hydrochloride) [105628-07-7]

Research Use Only
HY-10341
MedChem Express
CAS Number105628-07-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.96
Molecular Weight327.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fasudil (Hydrochloride) [105628-07-7]
  • Delivery Days Customer
    10
  • CAS Number
    105628-07-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.96
  • Molecular Formula
    C14H18ClN3O2S
  • Molecular Weight
    327.83
  • Scientific Description
    Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 microM for ROCK1, IC50s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
  • SMILES
    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200