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Fasudil (Hydrochloride)

HY-10341
MedChem Express
CAS Number105628-07-7
Product group Chemicals
Estimated Purity99.96
Molecular Weight327.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fasudil (Hydrochloride) [105628-07-7]
  • Delivery Days Customer
    10
  • CAS Number
    105628-07-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.96
  • Molecular Formula
    C14H18ClN3O2S
  • Molecular Weight
    327.83
  • Scientific Description
    Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 microM for ROCK1 , IC 50 s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil Hydrochloride is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3] .
  • SMILES
    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200