The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA017577(FAT4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA017577(FAT4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
FAT4 Antibody
CSB-PA017577
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFAT4
Overview
- SupplierCusabio
- Product NameFAT4 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79633
- Target nameFAT4
- Target descriptionFAT atypical cadherin 4
- Target synonymsCDHF14, CDHR11, FAT-J, FATJ, HKLLS2, NBLA00548, VMLDS2, protocadherin Fat 4, FAT tumor suppressor homolog 4, cadherin family member 14, cadherin-related family member 11, fat-like cadherin protein FAT-J, putative protein product of Nbla00548
- HostRabbit
- IsotypeIgG
- Protein IDQ6V0I7
- Protein NameProtocadherin Fat 4
- Scientific DescriptionFAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by gamma secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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