Fatostatin

MedChem Express

Fatostatin [125256-00-0]

10

125256-00-0

Research Use Only

99.85

C18H18N2S

294.41

Fatostatin (125B11), a specific inhibitor of SREBP activation , impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin decreases the transcription of lipogenic genes in cells. Fatostatin possesses antitumor properties, and lowers hyperglycemia in ob/ob mice [1] [2] .

CCCC1=NC=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=C1

-20°C,2°C to 8°C

12352200