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Fatostatin (hydrobromide)

HY-14452A
MedChem Express
CAS Number298197-04-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.43
Molecular Weight375.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fatostatin (hydrobromide) [298197-04-3]
  • Delivery Days Customer
    10
  • CAS Number
    298197-04-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.43
  • Molecular Formula
    C18H19BrN2S
  • Molecular Weight
    375.33
  • Scientific Description
    Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation , impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice [1] [2] .
  • SMILES
    CCCC1=NC=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=C1.[H]Br
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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