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FB23 [2243736-35-6]

FB23 [2243736-35-6]

T8874
TargetMol Chemicals
CAS Number2243736-35-6
DownloadMSDS
Product group Chemicals
Molecular Weight377.22
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    FB23 [2243736-35-6]
  • Delivery Days Customer
    4
  • CAS Number
    2243736-35-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    FB23
  • Molecular Formula
    C18H14Cl2N2O3
  • Molecular Weight
    377.22
  • Scientific Description
    FB23 directly binds to FTO and selectively inhibits FTOs m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.)
  • Shelf life instruction
    3 years
  • SMILES
    Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Huang Y et al., 2019 Apr 15, Cancer Cell
    Read more