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FBLIM1 antibody [N3C3]

Research Use Only
GTX116584
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetFBLIM1
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Overview

  • Supplier
    GeneTex
  • Product Name
    FBLIM1 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID54751
  • Target name
    FBLIM1
  • Target description
    filamin binding LIM protein 1
  • Target synonyms
    CAL; CSX-associated LIM; FBLP1; FBLP-1; filamin-binding LIM protein 1; MIG2-interacting protein; migfilin; mitogen-inducible 2 interacting protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8WUP2
  • Protein Name
    Filamin-binding LIM protein 1
  • Scientific Description
    This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Migfilin supports hemostasis and thrombosis through regulating platelet alphaIIbbeta3 outside-in signaling. Zhou Y et al., 2020 Nov 1, Haematologica
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