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FBW7 antibody

Research Use Only
ORB67185
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetFBXW7
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Overview

  • Supplier
    Biorbyt
  • Product Name
    FBW7 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:3000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID55294
  • Target name
    FBXW7
  • Target description
    F-box and WD repeat domain containing 7
  • Target synonyms
    AGO; archipelago; CDC4; F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila); F-box protein FBW7; F-box protein FBX30; F-box protein SEL-10; F-box/WD repeat-containing protein 7; FBW6; FBW7; FBX30; FBXO30; FBXW6; hAgo; hCdc4; homolog of C elegans sel-10; SEL10; SEL-10
  • Host
    Rabbit
  • Protein IDQ969H0
  • Protein Name
    F-box/WD repeat-containing protein 7
  • Scientific Description
    Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203