WB analysis of human spleen tissue lysate using GTX31424 FBXL16 antibody. Working concentration : (A) 0.5 and (B) 1 μg/ml
WB analysis of human spleen tissue lysate using GTX31424 FBXL16 antibody. Working concentration : (A) 0.5 and (B) 1 μg/ml
FBXL16 antibody
GTX31424
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFBXL16
Overview
- SupplierGeneTex
- Product NameFBXL16 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.5 - 1 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID146330
- Target nameFBXL16
- Target descriptionF-box and leucine rich repeat protein 16
- Target synonymsC16orf22, Fbl16, c380A1.1, F-box/LRR-repeat protein 16
- HostRabbit
- IsotypeIgG
- Protein IDQ8N461
- Protein NameF-box/LRR-repeat protein 16
- Scientific DescriptionMembers of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Morel M, Shah KN, Long W. The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7. J Biol Chem. 2020,295(23):7970-7980. doi: 10.1074/jbc.RA120.012658Read this paper
Datasheet
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Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX120503/GTX120503_40387_20160309_IHC-P_R_w_23060519_996.webp)
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