FBXL17 antibody [C1C3]
GTX119211
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetFBXL17
Overview
- SupplierGeneTex
- Product NameFBXL17 antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.76 mg/ml
- ConjugateUnconjugated
- Gene ID64839
- Target nameFBXL17
- Target descriptionF-box and leucine rich repeat protein 17
- Target synonymsFbl17; F-box only protein 13; F-box/LRR-repeat protein 17; Fbx13; FBXO13
- HostRabbit
- IsotypeIgG
- Protein IDQ9UF56
- Protein NameF-box/LRR-repeat protein 17
- Scientific DescriptionMembers of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation. Mason B et al., 2020 Jul, Cell Mol Life SciRead more