FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse heart. FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
![FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX119211/GTX119211_44146_20210507_IHC-P_M_1_w_23060519_807.webp "FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm in mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX119211/GTX119211_40352_20150806_IHC-P_M_w_23060519_962.webp "FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm in mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FBXL17 antibody [C1C3] (GTX119211) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX119211/GTX119211_44146_20201204_WB_23121122_199.webp "Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FBXL17 antibody [C1C3] (GTX119211) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse heart. FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
FBXL17 antibody [C1C3]
GTX119211
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetFBXL17
Overview
- SupplierGeneTex
- Product NameFBXL17 antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.76 mg/ml
- ConjugateUnconjugated
- Gene ID64839
- Target nameFBXL17
- Target descriptionF-box and leucine rich repeat protein 17
- Target synonymsFBXO13, Fbl17, Fbx13, F-box/LRR-repeat protein 17, F-box only protein 13
- HostRabbit
- IsotypeIgG
- Protein IDQ9UF56
- Protein NameF-box/LRR-repeat protein 17
- Scientific DescriptionMembers of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mason B, Flach S, Teixeira FR, et al. Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation. Cell Mol Life Sci. 2020,77(13):2605-2620. doi: 10.1007/s00018-019-03306-yRead this paper
Datasheet
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