
WB analysis of human frontal cortex (A) and rat (B) brain lysate using GTX17018 FBXL2 antibody, N-term. Dilution : 0.3μg/ml Loading : 35μg protein in RIPA buffer
FBXL2 antibody, N-term
GTX17018
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetFBXL2
Overview
- SupplierGeneTex
- Product NameFBXL2 antibody, N-term
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1microg/ml. IHC-P: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID25827
- Target nameFBXL2
- Target descriptionF-box and leucine rich repeat protein 2
- Target synonymsFBL2, FBL3, F-box/LRR-repeat protein 2, F-box protein FBL2/FBL3, F-box protein containing leucine-rich repeats
- HostGoat
- IsotypeIgG
- Protein IDQ9UKC9
- Protein NameF-box/LRR-repeat protein 2
- Scientific DescriptionThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- O'Brien ME, Londino J, McGinnis M, et al. Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter. Mol Cell Biol. 2020,40(12). doi: 10.1128/MCB.00040-20Read this paper





![Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FBXL2 antibody [N1], N-term (GTX104864) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX104864/GTX104864_44461_20211008_WB_22062919_885.webp)
